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University of Iowa News Release


Sept. 4, 2008

UI study on prostate enlargement seeks men age 45 and older

Men age 45 and older with benign prostatic hyperplasia -- also known as prostate enlargement -- are invited to participate in a University of Iowa research study comparing the safety and effectiveness of saw palmetto (a plant extract) to placebo (inactive substance) in reducing symptoms.

Eligible participants may have the following symptoms: frequent and/or urgent urination during the day or night, a weak or intermittent urinary flow, and/or straining to empty the bladder.

Men with a history of prostate surgery or a history of cancer, except for successfully treated skin cancer, are not eligible to participate.

Participation involves a screening visit, followed by visits every one, two or three months at UI Hospitals and Clinics over about 18 months. Participants will randomly be assigned to take increasing doses of saw palmetto or a placebo. Study medication(s) and all study tests will be provided at no cost. Compensation for parking is available.

The UI is one of 11 sites participating in this study, which will involve about 350 men overall. The investigation is funded by the National Institutes of Health and is part of a program on Complementary and Alternative Medicine for Urologic Symptoms.

The lead investigator at the UI site is Karl Kreder, M.D., professor of urology at the UI Roy J. and Lucille A. Carver College of Medicine.

For more information, call toll-free 866-236-1432 or 319-356-1111 or email

NOTE TO EDITORS: This release about a UI clinical study originally was distributed May 13, 2008. Participants still are welcome to participate in the study.

STORY SOURCE: University of Iowa Health Science Relations, 5137 Westlawn, Iowa City, Iowa 5224-1178

MEDIA CONTACT: Becky Soglin, 319 335-6660