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University of Iowa News Release


Oct. 24, 2007

Study seeks men, women 18 and older with overactive bladder problems

Men and women age 18 and older who have been experiencing overactive bladder symptoms for at least the past three months are invited to participate in a University of Iowa research study of medications for symptoms.

The study will compare the safety and effectiveness of an investigational medication to a placebo (inactive substance) in reducing symptoms.

Overactive bladder symptoms include taking more than eight trips to the bathroom in one day, strong and sudden urges to urinate and/or the inability to hold urine until getting to the toilet. People with a history of interstitial cystitis and men who have had prostate cancer are not eligible to participate.

The study will involve approximately five visits to UI Hospitals and Clinics over 12 weeks. Participants will be randomly assigned to take either the study medication or a placebo. All participants will be asked to keep a bladder diary and complete several quality-of-life questionnaires about their bladder health.

Qualified participants will receive study medication or placebo and all study-related medical care at no cost and may be compensated for time and travel.

The UI is one of more than 100 centers in the United States taking part in the study, which is funded by a major pharmaceutical company.

The lead investigator is Elizabeth Takacs, M.D., clinical assistant professor of urology in the UI Roy J. and Lucille A. Carver College of Medicine.

For more information, call the study coordinators at 319-384-5769 (Diane Meyerholz) or 319-384-9265 (Mary Eno). You may also e-mail the study coordinators at or

STORY SOURCE: University of Iowa Health Science Relations, 5137 Westlawn, Iowa City, Iowa 52242-1178

MEDIA CONTACTS: Diane Meyerholz, study coordinator, 319-384-5769 or 866-236-1432 or; Mary Eno, study coordinator, 319-384-9265 or 866-309-0834 or; Becky Soglin, Health Science Relations, 319-335-6660,