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University of Iowa News Release


July 16, 2007

UI Study Invites Adults With Interstitial Cystitis

Men and women age 18 and older with interstitial cystitis that has not responded to three or more different types of treatments in the previous six months are invited to participate in a University of Iowa research study.

The study will investigate the safety and effectiveness of an investigational immunosuppressant called CellCept in treating interstitial cystitis, sometimes known as painful bladder syndrome. People with the condition experience extreme bladder/pelvic pain and urinary frequency and urgency.

Women who are pregnant or breastfeeding and men with a history of prostate cancer are not eligible to participate.

Study participation will involve 11 visits, including screening visits, to UI Hospitals and Clinics over approximately 20 weeks. Eligible participants will randomly be assigned to take the study medication or a placebo (inactive substance). Each participant will have a two out of three chance of being assigned to take CellCept.

Physical exams, study medication, blood and urine tests, and cystoscopy (if needed) will be provided at no cost. Parking passes will be provided for clinic visits. Participants and/or their medical/hospital insurance carrier will remain responsible for regular medical care expenses.

The UI is one of 11 centers taking part in the study, which is sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health.

Approximately 30 individuals will take part in the study at the UI site, where the lead investigator is Karl Kreder, M.D., professor of urology at the UI Roy J. and Lucille A. Carver College of Medicine.

For more information, call toll-free 866-309-0834 or 319-384-9265 or e-mail

STORY SOURCE: University of Iowa Health Science Relations, 5137 Westlawn, Iowa City, Iowa 52242-1178

STUDY CONTACT: Mary Eno, 866-309-0834 or 319-384-9265 or

MEDIA CONTACT: Becky Soglin, 319-335-6660,

PRONUNCIATION NOTE: The bladder condition "Interstitial Cystitis" is pronounced "Inter-STITCH-e-al Sist-I-tis."