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University of Iowa News Release

Sept. 8, 2004

UI Behavior Treatment Study Seeks People With Dementia

A University of Iowa Health Care study on the use of the medication risperidone for behavior problems in persons with memory disorders (dementia) invites eligible people to participate. The investigation focuses on the difference between using the medication continuously or using it with breaks in its use to treat the behavior problems, not the memory disorder.

Adults ages 40 to 95 who have been diagnosed with Alzheimer's disease and have difficulties such as hallucinations, unfounded ideas or worries, or problems with being angry, restless, nervous and irritable for no apparent reason are eligible to participate. However, people who also have a history of stroke or a significant neurological condition such as Parkinson's disease are not eligible to participate. The person who assists the participant in decision-making, such as a family member or aide, is invited to participate as well.

The study involves approximately 17 visits over the course of one year. The visits may occur at the University of Iowa or may occur within the participant's residence, if desired. Participants will be provided medication free of charge and meet with the study team to assess specific problems and evaluate any changes in symptoms, caregiver burden and participant's overall health.

The UI is one of several institutions participating in this multi-center study. The UI portion of the investigation is led by Susan Schultz, M.D., associate professor of psychiatry at the UI Roy J. and Lucille A. Carver College of Medicine. Schultz also is a staff physician with the Iowa City Veterans Affairs Medical Center.

For more information, contact Karen Ekstam, study coordinator in psychiatry, at 319-353-5158 or

University of Iowa Health Care describes the partnership between the UI Roy J. and Lucille A. Carver College of Medicine and UI Hospitals and Clinics and the patient care, medical education and research programs and services they provide. Visit UI Health Care online at

STORY SOURCE: University of Iowa Health Science Relations, 5137 Westlawn, Iowa City, Iowa 52242-1178

Interested Participants: Karen Ekstam (study coordinator), 319-353-5158,

Media Only: Becky Soglin, 319-335-6660