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University of Iowa News Release

Nov. 4, 2004

UI Invites Women To Participate In Cervical Cancer Vaccine Study

Young women ages 15 to 25 are invited to participate in a University of Iowa Health Care study to test the efficacy of an investigational vaccine for human papillomavirus (HPV) types 16 and 18. These types of HPV are associated with nearly three out of every four cases of cervical cancer.

Those interested in participating must be healthy overall and must not be pregnant or planning to conceive during the first eight months of the study. Participants must be willing to make 10 visits over the course of four years to the UI Family Planning Clinic. Participants will be chosen randomly to receive either the HPV vaccine or Hepatitis A vaccine, which will serve as the control.

The study includes gynecological exams, at no cost, that will test for the presence of HPV infection or precancerous cells. Compensation will be provided.

This study will be conducted in approximately 15 different countries and involve approximately 13,000 adolescent and young adult women. At the UI, where 100 women are expected to participate, the principal investigator is Kevin Ault, M.D., associate professor of obstetrics and gynecology.

For more information, call Tracy Peters, UI research nurse, or Tobey Kelly, at 319-384-4531 and ask about the HPV vaccine trial.

University of Iowa Health Care describes the partnership between the UI Roy J. and Lucille A. Carver College of Medicine and UI Hospitals and Clinics and the patient care, medical education and research programs and services they provide. Visit UI Health Care online at

STORY SOURCE: University of Iowa Health Science Relations, 5137 Westlawn, Iowa City, Iowa 52242-1178

CONTACTS: Interested Participants: Tracy Peters, 319-384-4531,
Media: Becky Soglin, 319-335-6660,