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University of Iowa News Release

April 29, 2004

Holden Comprehensive Cancer Center Leadership Appointments Made

Three University of Iowa faculty members have been appointed to leadership positions in the Holden Comprehensive Cancer Center at the UI. The appointments are effective immediately.

Larry Oberley, Ph.D., professor of radiation oncology in the UI Roy J. and Lucille A. Carver College of Medicine, will serve as deputy director of the Holden Cancer Center. Oberley also directs the Free Radical and Radiation Biology Graduate Program. His research focuses on the role of reactive oxygen species, reactive nitrogen species and antioxidants in human diseases. His team studies how a particular protein from a tumor suppressor gene might be used to treat cancer.

Gail Bishop, Ph.D., UI Carver College of Medicine Distinguished Professor of Microbiology and Internal Medicine, is the new associate director for basic research. Bishop's research focuses on an important component of the immune system -- a protein called CD40 found in the membranes of certain white blood cells. Her research has therapeutic implications related to how the immune system responds to cancer and for lymphomas that are associated with severely weakened immune systems. Bishop is also a researcher with the Iowa City Veterans Affairs Medical Center.

John Lowe, Dr.P.H., professor and head of the Department of Community and Behavioral Health in the UI College of Public Health, will be associate director for population science. His research pursuits include cancer prevention and control, and smoking cessation and prevention. Lowe also directs the Iowa Tobacco Research Center at the UI, which operates Quitline Iowa, the state's toll-free smoking cessation hotline.

"Professors Oberley, Bishop and Lowe are all extremely accomplished researchers and leaders. They will help the Cancer Center advance the research of our many talented investigators -- studies which are geared towards understanding cancer, and using that understanding to develop new approaches to cancer prevention and treatment. I am thrilled to have them in these leadership roles," said George Weiner, M.D., director of the Holden Comprehensive Cancer Center, the Dr. C.E. Block Chair of Cancer Research and professor of internal medicine.

The Holden Comprehensive Cancer Center is Iowa's only National Cancer Institute (NCI)-designated comprehensive cancer center. NCI-designated comprehensive cancer centers are recognized as the leaders in developing new approaches to cancer prevention and cancer care, conducting leading edge research and educating the public about cancer. Visit the center online at

University of Iowa Health Care describes the partnership between the UI Roy J. and Lucille A. Carver College of Medicine and UI Hospitals and Clinics and the patient care, medical education and research programs and services they provide. Visit UI Health Care online at

STORY SOURCE: University of Iowa Health Science Relations, 5137 Westlawn, Iowa City, Iowa 52242-1178

MEDIA CONTACT: Becky Soglin, 319-335-6660,