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Release: Jan. 22, 2003

UI invites women to participate in cervical cancer vaccine study

Women ages 16 to 23 are invited to participate in a University of Iowa Health Care clinical trial to help determine the effectiveness and safety of a vaccine for human papillomavirus (HPV). The virus is associated with most cases of cervical cancer.

Women interested in participating in the trial must be in general good health and must not be pregnant or planning to conceive during the first seven months of the study. Participants must be willing to make approximately eight visits to the UI Family Planning Clinic at UI Hospitals and Clinics. Over the course of the study, participants will receive three injections of either vaccine or a placebo.

Follow-up includes up to four years of gynecological exams that will test for the presence of HPV infection or precancerous cells. In addition, routine gynecologic care, contraception and compensation will be provided.

The study is led by Kevin A. Ault, M.D., UI assistant professor of obstetrics and gynecology, who has led previous UI studies on cervical cancer vaccines. An effective vaccine will likely include several HPV strains.

For more information, call Tracy Peters, UI research nurse, at (319) 384-4531 and ask about the HPV vaccine trial.

University of Iowa Health Care describes the partnership between the UI Roy J. and Lucille A. Carver College of Medicine and UI Hospitals and Clinics and the patient care, medical education and research programs and services they provide. Visit UI Health Care online at