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Release: Oct. 9, 2002

Women invited to participate in UI research study on menopause and memory

The University of Iowa College of Public Health is conducting a five-month research study on cognitive function (memory and attention) and menopause. The Menopause and Memory Research Study will look at whether hormone replacement therapy affects memory and attention.

"Despite recent research study findings and media publicity, hormone replacement therapy will continue to be prescribed to treat menopausal symptoms such as hot flashes or memory complaints," said Susan Johnson, M.D., UI professor of obstetrics and gynecology and principal investigator for the study.

According to Johnson, many women notice changes in their memory and attention around the time they go through menopause. "Although estrogen is often used to treat these symptoms, we do not yet have evidence that this is effective," she said.

To qualify for the study, women must:

-- Be ages 45 to 55;

-- Have had their last menstrual period six months to three years ago;

-- Have a uterus (no hysterectomy); and

-- Not be currently taking hormone replacement therapy.

Study participants must also be non-smokers and must have a high school diploma or GED.

There will be four research clinic appointments in Iowa City during the five-month study. Study participants will receive either a combination hormone pill (estrogen plus progesterone) or a placebo (inactive pill). Testing, such as mammograms, Pap and pelvic exams, and a physical exam will be provided free of charge. Compensation is available.

For more information about this research study, call (319) 384-5055 or toll-free (800) 348-4692.