CONTACT: DAVE PEDERSEN
Iowa City IA 52242
(319) 335-8032; fax (319) 384-4638
Release: Jan. 28, 2002
Women invited to participate in UI hormone replacement therapy study
IOWA CITY, Iowa -- The University of Iowa College of Public Health is beginning
a new, 28-week research study comparing two forms of hormone replacement therapy
that are currently available by prescription. Women, ages 40 to 65, who have
gone at least six months since their last menstrual period are invited to
To qualify, women must have their uterus present and must not be currently
taking any kind of hormone replacement therapy. Participants in the UI study
will be asked to make five visits to the study clinic in Iowa City. All study
participants will receive one of the two active study medications being tested.
There will be no placebo (inactive pill) given in this study. Testing such
as mammograms, Pap and pelvic exams, and a physical exam will be provided
free of charge. Compensation is available.
"Hormone replacement therapy is currently prescribed for the treatment
of hot flashes, other symptoms associated with menopause and the prevention
of osteoporosis," said Helmut Schrott, M.D., UI professor of epidemiology
and principal investigator for the study.
However, according to Schrott, hormone replacement therapy use among women
overall is low because of the side effects. "If side effects can be reduced,
women might be more able to stay on this type of therapy," he said.
One of the most common side effects of hormone replacement therapy is unwanted
vaginal bleeding or spotting. The UI study will compare the two types of hormone
replacement therapy for incidences of bleeding or spotting.
For more information about this research study, call (319) 384-5055 or toll-free