CONTACT: BECKY SOGLIN
Iowa City IA 52242
(319) 335-6660; fax (319) 384-4638
Release: Oct. 9, 2001
NOTE TO EDITORS: This release was originally distributed Aug. 29, 2001. Participants
still are needed. This release can be used anytime THROUGH NOV. 30, 2001.
Women with bladder overactivity invited to be in UI study
IOWA CITY, Iowa -- Women with certain bladder problems are invited to participate
in a University of Iowa Health Care Study to test the effectiveness of a medication
to alleviate the symptoms and improve quality of life.
Participants must be age 18 and older and have experienced over the past
three months either bothersome urinary urgency (feeling the urgent need to
void for fear of leakage) or urge urinary incontinence (the involuntary loss
of urine preceded by urgency). In addition, eligible participants must have
urinary frequency with an average voiding of every two hours or less, which
will be confirmed at a preliminary study visit.
Women who are not eligible for the study include those already taking regular
medication for urge incontinence within one month prior to the study. In addition,
participants must not be taking any antidepressants and must not be pregnant
or planning to get pregnant during the study period. Women on certain antianxiety
drugs are eligible to participate.
Participants will be asked to make a total of six visits to the UI Hospitals
and Clinics in Iowa City, including two initial evaluations that will determine
whether each person fully qualifies for the study. The additional four visits
will take place over a 12-week period. Half of the study participants will
receive the medication, while half will receive a placebo (sugar pill). Compensation
will be provided.
The study is being conducted by Karl Kreder, M.D., UI professor of urology
and director of the UI Division of Urodynamics and Reconstructive Urology,
and Ingrid Nygaard, M.D., UI associate professor of obstetrics and gynecology
and director of the UI Urogynecology Program.
For more information contact, Mary Eno, UI research associate in urology,
at (319) 384-9265 or Debra Brandt, UI research associate in gynecology, at
University of Iowa Health Care describes the partnership between
the UI College of Medicine and the UI Hospitals and Clinics and the patient
care, medical education and research programs and services they provide. Visit
UI Health Care online at www.uihealthcare.com.