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Release: April 12, 2001

NOTE TO EDITORS: The following study is based at the University of Iowa but accepts participants from any of the 48 contiguous states.

People with certain heart defects are invited to participate in study

IOWA CITY, Iowa -- People ages 40 and younger who have certain nonsyndromic heart defects and live anywhere in the 48 contiguous states are invited to participate in a University of Iowa study aimed at identifying risk factors for heart defects.

People who have secundum atrial septal defect (ASD), perimembraneous ventricular septal defect (VSD) or atrioventricular (AV) canal defect are eligible to participate. The defect must be medically documented, and the person (or guardian, if prospective participant is a child) must be willing to release medical records that document the defect. Eligible participants must not have any other syndromes or genetic defects.

Participation will require a blood sample be taken from the participant and one or both biological parents. These samples will be collected at local hospitals at no charge to the participant or family members. In addition, the individual or parent (if participant is a child) will be asked to provide a medical history over the phone.

By learning more about genetics and family history related to heart defects, the researchers hope to prevent heart defects in future generations of children. The study is sponsored by the National Institutes of Health.

For more information, call the UI Specialized Center of Research in Congenital Heart Disease toll-free at (877) 226-8105 or visit the study Web site at

University of Iowa Health Care describes the partnership between the UI College of Medicine and the UI Hospitals and Clinics and the patient care, medical education and research programs and services they provide.