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Release: May 2, 2000

UI pharmacology researcher receives $1.2 million grant

IOWA CITY, Iowa -- A University of Iowa Health Care researcher has received a five-year, $1.2 million grant to study a hormone involved in reproduction.

Mario Ascoli, Ph.D., UI professor of pharmacology, will lead a research investigation focusing on the cellular and molecular basis of the actions of a hormone called follitropin or FSH.

FSH is involved in the regulation of reproductive functions in both males and females. FSH is important for follicular growth in the ovary and for spermatogenesis in the testis. It is clinically used in the treatment of certain forms of infertility in both females and males.

"Whereas our work addresses the cellular and molecular bases of the actions of FSH, it may eventually help us better understand how to use this hormone in a clinical setting," Ascoli said.

The grant comes from the National Institute of Child Health and Human Development, which is part of the National Institutes of Health.

University of Iowa Health Care describes the partnership between the UI College of Medicine and the UI Hospitals and Clinics and the patient care, medical education and research programs and services they provide.