CONTACT: BECKY SOGLIN
2130 Medical Laboratories
Iowa City IA 52242
(319) 335-6660; fax (319) 335-8034
Release: Jan. 28, 2000
Men invited to participate in UI urinary frequency
(Editors' Note: Please do not use this release
after Feb. 21, 2000.
IOWA CITY, Iowa -- University of Iowa Health Care
researchers invite men with bladder overactivity and coexisting mild to moderate
bladder outlet obstruction to participate in a study of the safety and efficacy
of a medication to treat the condition.
Participants must be age 40 or older and experiencing
urinary frequency (averaging 8 or more urinations daily) and urinary urgency
or urge incontinence. Men with previous bladder or prostate surgery or instrumental
treatment for prostate problems are not eligible to participate. In addition,
men must not have experienced urinary retention within the past 12 months.
The study will last 12 weeks during which participants
must be willing to make four visits to the UI Hospitals and Clinics and take
either the study medication (tolterodine) or a placebo. Compensation will
Men who have enlarged prostates, which typically occurs
with age, may experience bladder control problems, said Karl J. Kreder, M.D.,
UI professor of urology and lead investigator for UI participation in the
"The medication under investigation is designed to
relax the bladder," said Kreder, who is director of the UI Urodynamics and
Reconstructive Urology division.
For more information about the study, contact Mary
Eno, research nurse, at (319) 384-9265.
University of Iowa Health Care describes the partnership
between the UI College of Medicine and the UI Hospitals and Clinics and the
patient care, medical education and research programs and services they provide.