CONTACT: BECKY SOGLIN
2130 Medical Laboratories
Iowa City IA 52242
(319) 335-6660; fax (319) 335-8034
Release: Feb. 21, 2000
UI to begin second cervical cancer vaccine study
IOWA CITY, Iowa -- University of Iowa Health Care researchers will begin
a second clinical trial this month to help determine the effectiveness and
safety of a vaccine for a type of human papillomavirus (HPV), which is associated
with many cases of cervical cancer.
The trial will involve women ages 16 to 23. Women interested in participating
in the trial must be in general good health and must not be pregnant or planning
to conceive while enrolled in the study, which will last approximately seven
Participants must be willing to make approximately five visits to the UI
Family Planning Clinic at the UI Hospitals and Clinics, during which they
will receive the vaccine or a placebo. Follow-up includes seven months of
gynecological exams to test participants for the presence of HPV infection
or precancerous cells. Compensation will be provided.
Nearly all cervical cancer cases in women are associated with HPV infection,
said Kevin A. Ault, M.D., UI assistant professor of obstetrics and gynecology
and the study's lead investigator.
"Any final cervical cancer vaccine will likely include several HPV
strains because a vaccine against one strain does not protect against another,"
Ault said. Several other clinical trials are underway in the United States
For more information, call Tracy Peters, research nurse, at (319) 356-2719
and ask about the HPV vaccine trial.
HPV infection often goes unnoticed because the symptoms are largely "silent."
However, an untreated individual can easily spread the infection to other
sexual partners over years or decades.
Cervical cancer annually causes nearly 5,000 deaths in the United States
and 500,000 worldwide. In Iowa, nearly 150 women are diagnosed with cervical
cancer each year.
University of Iowa Health Care describes the partnership between the
UI College of Medicine and the UI Hospitals and Clinics and the patient care,
medical education and research programs and services they provide.